In the PPI network analysis of BST, HMOX1, CXCL8, CCL2, IL6, MAPK8, CASP3, PTGS2, AKT1, IL1B, MYC, TP53, IFNG, and IL2 were screened out, all of which are core targets in the treatment of vitiligo. The gene discussed is AKT1; the disease is vitiligo.