In the PPI network analysis of BST, HMOX1, CXCL8, CCL2, IL6, MAPK8, CASP3, PTGS2, AKT1, IL1B, MYC, TP53, IFNG, and IL2 were screened out, all of which are core targets in the treatment of vitiligo. Here, CASP3 is linked to vitiligo.