The bar plot presents the top 30 potential hub genes through which FZHY acts on CKD, such as IL-6 (Feigerlová & Battaglia-Hsu., 2017), EGFR (Rayego-Mateos et al., 2018), MAPK8, and FOS (Grynberg et al., 2017). This evidence concerns the gene MAPK8 and chronic kidney disease.