DCLK1 and malignant colon neoplasm: Doublecortin-like kinase1 (DCLK1), a characteristic gene of tuft cells, was associated with progression of gastric cancer, pancreatic cancer, colon cancer, and renal cancer (Weygant et al., 2016; Ge et al., 2018), and involved in the initiation, growth, metastasis, epithelial-mesenchymal transition (EMT), and stemness of the tumor (Westphalen et al., 2017; Sureban et al., 2011; Ito et al., 2016).