CGRP, ADM, and ADM2 have been shown to promote vascular development and tumor growth (Toda et al., 2008; Smith et al., 2009; Zheng et al., 2010; Mishima et al., 2011; Aslam et al., 2012; Hong et al., 2012; Kurashige et al., 2014; Russell et al., 2014; McIlvried et al., 2022). The gene discussed is ADM2; the disease is neoplasm.