It can be seen that 17 major cluster labels were marked, including osteosarcopenia, irisin, calcium, peripheral quantitative computed tomography, accelerometer, sarcopenia, microgravity, vitamin d supplementation, whole body vibration, biochemical markers of bone turnover, obesity, sclerostin, older men, body mass, juvenile idiopathic arthritis, bulimia and male athlete triad. This evidence concerns the gene SOST and obesity due to melanocortin 4 receptor deficiency.