CASP3 and infection: Figure 8A shows that the amount of cytoplasmic capsid label was visibly decreased in the presence of caspase 3 inhibitor in comparison to untreated NLFK cells at 24 hpi. The image data analysis using capsid localization classes described above (Figure 6C) confirmed that the nuclear egress of capsids was significantly decreased during caspase 3 inhibition. Simultaneously, capsid retention close to the NE was increased. Interestingly, the early steps of infection shown by capsid localization into cytoplasmic vesicles were reduced in the presence of the inhibitor (Figure 8B).