These data suggest that zeb2 could be another candidate gene to compensate for the loss of chd7. SOX2, which is mutated in Alagille, Pallister–Hall, and Feingold syndromes, regulates similar genes that are misexpressed in neural stem cells after shRNA-mediated knockdown with Chd7 (Lettieri et al., 2021). Here, SOX2 is linked to Feingold syndrome type 1.