Mouse models of ALMS have included a whole-body Alms1 knockout (Almsflin/flin) (Geberhiwot et al., 2021) and the fat aussie mouse which carries a spontaneous 11 bp deletion resulting in a frameshift and truncating mutation in Alms1 (Arsov et al., 2006; Kim et al., 2020). The gene discussed is ALMS1; the disease is Alstrom syndrome.