NECTIN1 and Intellectual disability: Mutations in nectin-1 gene cause cleft lip/palate ectodermal dysplasia, Margarita Island ectodermal dysplasia, and Zlotogora–Ogür syndrome, which is characterized by cleft lip/palate, syndactyly, intellectual disability, and ectodermal dysplasia (Suzuki et al., 2000; Sozen et al., 2001).