Although cells with a mutant CD36 (CD36-K164A) can generate some lymph node metastasis, the lesions have cells with increased content of LD (Pascual et al., 2017), indicating that CD36 is essential for the metabolic reprogramming coupled to the adapting to the metastatic niche. This evidence concerns the gene CD36 and metastatic malignant neoplasm in the lymph nodes.