In the univariate analysis, serum levels of hemoglobin (OR: 0.953, 95% CI: 0.918–0.989, P = 0.010), BUN (OR: 1.060, 95% CI: 1.002–1.122, P = 0.044), albumin (OR: 0.863, 95% CI: 0.751–0.992, P = 0.038), and D-dimer (OR: 1.184, 95% CI: 1.073–1.308, P = 0.001) were risk factors for in-hospital death in AUGIB patients with myocardial injury. The gene discussed is ALB; the disease is injury.