Unadjusted Model: MedDiet Score; Fully Adjusted Model: MedDiet Score, age, education, family history, APOE, physical activity, smoking, sleep, BMI, hypertension, hypercholesterolemia, hyperglycaemia, diabetes, stroke, antihypertensive medication use, diabetic medication use, Mediterranean region. The gene discussed is APOE; the disease is Hypercholesterolemia.