Figure 1B shows the correlation between SIRT gene expression in TCGA gliomas. The ROC curve tests showed that SIRT2 (AUC = 0.811) and SIRT6 (AUC = 0.805) can effectively distinguish glioma samples from normal brain tissue samples (Figure 1C). Figure 1D shows SIRT gene expression in gliomas and normal brain tissues in the HPA database. The gene discussed is SIRT6; the disease is central nervous system cancer.