Clinical treatments for stroke, for instance, include rapid infusion of tissue plasminogen activator (tPA, chemical thrombus disaggregation) within 4 h last-known-well, or catheter-based mechanical thrombectomy (MT, surgical clot removal) in the hyper-acute phase between 4 h and recently-extended 24 h last-known-well (Powers et al., 2018). The gene discussed is PLAT; the disease is stroke disorder.