We noticed that increased PDL1 expression was associated with increased cellular resistance to chemotherapy drugs such as Tamoxifen and Nilotinib; we also observed inverse associations of multiple genes to these drugs, Furthermore, PDL1 was associated with increased sensitivity of cells to Dasatinib (treatment for mantle cell lymphoma and chronic lymphocytic leukemia), while CTLA4 was associated with increased resistance of cells to Dasatinib. The gene discussed is CD274; the disease is mantle cell lymphoma.