We finally obtained 10 genes that are closely associated with the prognosis of DLBCL patients, including CXCL9, TIFAB, C3, VCVAM1, ZBE, D2, TIMD4, KLHL14, TNFRSF9, FCRL3, and PLEKHG1. This evidence concerns the gene KLHL14 and diffuse large B-cell lymphoma.