The fact that some of these EV proteins (e.g., PBIP1 and APOC2), mRNAs (e.g., DLC1 and MTO1), and miRNA (e.g., hsa-miR-99a-5p and hsa-mir-203a-3p) are present in the EVs of EC or SI tumor patients, exclusively, suggests that they are able to fulfill that unique role. Here, APOC2 is linked to neoplasm.