engineered multifunctional and colloidally stable bioinorganic nanoparticles composed of polyelectrolyte-albumin complex and MnO2 nanoparticles (A-MnO2 NPs), which can effectively increase tumor oxygenation by triggering decomposition of tumor endogenous H2O2 and significantly inhibit the tumor growth in company with radiotherapy (Figure 3D) (66). The gene discussed is ALB; the disease is neoplasm.