Tumor latency was significantly decreased in K8iKOR-Wnt1 mice (12.5 weeks after tamoxifen injection, p<0.0001) (Figure 2B) similar to the DN-Wnt1 mouse line as previously reported (16.6 weeks, p<0.0001) (Figure 2B) (19). The gene discussed is WNT1; the disease is neoplasm.