Consistent with these data, recent analyses using two different patient databases, The Cancer Genome Atlas (TCGA) and the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC), have revealed low IGF1R expression is associated with undifferentiated, triple-negative breast cancer (TNBC) and worse overall survival (16, 17). The gene discussed is IGF1R; the disease is triple-negative breast carcinoma.