Figure 3F is showcasing normalized phosphorylated to total HDAC4 ratio. These observations are depicting the selective effects of Que to reduce pSer246-HDAC4 expression in Que-treated diabetic rats. The relative cardiac tissue expression of pro B-type natriuretic peptide (BNP), a significant marker of progressed heart failure, remained unaffected neither by diabetes or quercetin (Figure 3C). Representative Western blots are displayed in Figure 3G. This evidence concerns the gene NPPB and diabetes mellitus.