CCL5 and neoplasm: M-MDSCs can promote a pool of tumor-associated DCs by differentiating into inflammatory DCs (inf-DCs), which appear to have specific phenotypes and are key components of antitumor responses.26The chemokine CCL5 was shown to play an important role in granulocyte and monocyte differentiation,27and we hypothesized that inhibition of CCL5 in tumor-bearing mice might reverse the monocyte-to-granulocyte differentiation trend, thereby enhancing MDSC- The immune function of DCs, but the specific mechanism needs to be further explored.