And among patients with HNSCC (head and neck squamous cell carcinoma) in complete remission and those who failed postoperative radiotherapy, FN1 overexpression plays an important role in the development, prognosis, and radioresistance of HNSCC and is a potential new biomarker for predicting poor prognosis and radioresistance in patients with head and neck squamous cell carcinoma [14]. The gene discussed is FN1; the disease is head and neck squamous cell carcinoma.