CD40LG and infection: Serum IgG binding responses to both LASV GP and NP waned after eight years while IgM responses, as expected, were absent one year post-infection (Fig. 4c–f) The peak mean IgG binding antibody response was seen amongst individuals tested four years post-infection, which was significant for anti-NP antibodies (P = 0.001) and not for anti-GP antibodies.