STING1 and neoplasm: reported a novel Hf‐based cationic nMOF, Hf–DBBF–Ir (DBB = 4,4′‐di(4‐benzoato)‐2,2′‐bipyridine), by mediating efficient RT–RDT to generate immunogenic tumor antigens and DAMPs and deliver anions in pathogen‐associated molecular patterns (PAMPs) CpG for nonviral in situ vaccination.[137] The results demonstrate that DAMP‐induced cGAS–STING and CpG‐induced TLR pathways such as PAMP operate independently, suggesting that they may be activated simultaneously to achieve additive or synergistic effects on immune stimulation.