It has been reported that tumor cell‐derived exosomal PD‐L1 can inhibit tumor‐specific T‐cell activity.[24, 25, 38] In addition, we showed that 6J1 activated Rab27 to induce PD‐L1 secretion in EVs from tumor cells (Figure 5F–J). The gene discussed is CD274; the disease is neoplasm.