The induction of anorexia is a well-documented effect of PACAP (Mounien et al., 2009; Dore et al., 2013; Resch et al., 2013; Kocho-Schellenberg et al., 2014); our results are consistent in particular with previous report that intra-CeA infusion of PACAP causes anorexia and reduced body weight gain (Iemolo et al., 2015). This evidence concerns the gene ADCYAP1 and Anorexia.