There have also been reports of other similar childhood blistering disorders in IEI patients such as chronic granulomatous disease (CGD) with linear IgA dermatosis [23], auto-inflammation and phospholipase Cγ2 (PLCγ2)-associated antibody deficiency and immune dysregulation (APLAID) syndrome with early-onset blistering lesions [24], and SERPING1 mutation with bullous lesions at the site of angioedema [25] that are not discussed here. This evidence concerns the gene SERPING1 and angioedema.