Overexpression of miR-125b-2-3p may promote metastasis of clear cell renal cell cancer by targeting EGR1, leading to poor prognosis [21]; it also plays an important role in regulating the proliferation of colorectal cancer and oral squamous cell carcinoma by acting as a downstream target of long noncoding RNAs, XIST and AC007271.3 [22, 23]. This evidence concerns the gene EGR1 and oral cavity squamous cell carcinoma.