In order to confirm the role of SGOL2/RAB1A regulatory axis in prostate cancer, we constructed four cell models using SGOL2 knockdown lentivirus and RAB1A overexpression (OE) lentivirus (control group, shSGOL2 + RAB1A-OE group, shSGOL2 group, RAB1A-OE group). Here, SGO2 is linked to Familial prostate cancer.