Nevertheless, the presence of highly elevated glucose levels in combination with failure to thrive and impaired ETS in mitochondria may therefore make Uqcrh-KO mutant mice a valuable in vivo model for further in-depth investigation of mitochondrial diabetic cardiomyopathy and other multisystemic pathologies associated with hyperglycemia, such as sepsis. This evidence concerns the gene UQCRH and Failure to thrive.