Clearly, GATA3 was negatively correlated with CTL signature gene (IL2, CD8A, CCL5, GZMA, PRF1, IFNG, PTPRC, GZMM, RAB27A, XCL1, ICOS, TBX21, GZMB, GNLY, and IL12A) in breast cancer (Fig. 1D). This evidence concerns the gene PRF1 and breast carcinoma.