Lastly results from a phase I trial exploiting anti-HER2 CAR-T cells revealed partial response in 1 patient, SD in 7 patients for 8 weeks to 29 months and progressive disease in 8 patients (16 evaluable patients) with researchers highlighting that evaluation of anti-HER2 CAR-T cells in GBM patients in a phase 2b study is warranted (Brown et al. 2016). This evidence concerns the gene ERBB2 and glioblastoma.