Erythrocyte (CD235a) and endothelium (CD31) derived LEVs expression (MFI) were also significantly (CD235a, p = 0.016; CD31, p = 0.020) different between healthy donor and COVID-19 (+) patients (Fig. S5E, F), but the positive shift of CD41 population is more evident (Fig. 2D, S5D). The gene discussed is ITGA2B; the disease is COVID-19.