Specifically, VWF, F13A1 (factor XIII A subunit), F13B (factor XIII B subunit), FGA (alpha subunit of fibrinogen), FGB (beta component of fibrinogen), GP1BA (glycoprotein Ib-alpha)—were all procoagulant proteins and/or of platelet origin enriched in both LEVs and SEVs from COVID-19 (+) patients. Here, VWF is linked to COVID-19.