CST3 and cancer: The multivariable-adjusted HRs (Model 2) of all-cause, cardiovascular and cancer mortality with the lowest quartile (Q1) of cystatin C concentrations as the reference were 1.92 (1.62–2.28), 1.98 (1.48–2.65), and 1.62 (1.13–2.32), respectively, for the highest quartile (Q4) (all P for trends < 0.05) (Table 2).