HLA-DRB1 and type 1 diabetes mellitus: Associations between variants in class II proteins (HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ and HLA-DR expressed by B cells, antigen-presenting cells and activated T cells) have been identified for Graves’ disease (HLA-DR3), systemic lupus erythematosus (HLA-DR3), Hashimoto’s thyroiditis, myasthenia Gravis (HLA-DR3), Addison’s disease (HLA-DR3), rheumatoid arthritis (e.g. HLA-DRB1), coeliac disease (e.g. HLA-DR3-DQ2), multiple sclerosis (HLA-DR3) and type 1 diabetes (DR3)40,46.