KDM6B and gastric cancer: In addition, the results of clonogenic assay also showed that the clonogenic ability of gastric cancer cells is significantly enhanced after the ectopic expression of KDM6B compared with the control, but the clonogenic ability of GC cells transfected with the KDM6B enzymatic activity-deficient mutant plasmid (H1390A) did not change (Fig. 2E, and Supplementary Fig. 2C, D).