To investigate the effect of KDM6B on the migration ability of GC cells in vivo, we injected the cells that stably carry the construct, knockdown Lv-shKDM6B-MKN-45 or its negative control Lv-shNC-MKN-45 into nude mice via the tail vein to establish an in vivo tumor metastatic model. Here, KDM6B is linked to neoplasm.