AGT and hypertensive disorder: We have previously demonstrated a role for the SFO, OVLT and MnPO in the chronic hypertensive effects of “AngII hypertension” as lesion of each individual central structure attenuated the hypertensive effect of AngII during normal salt intake (Collister & Hendel, 2005; Hendel & Collister, 2005; Ployngam & Collister, 2007; Vieira et al., 2010).