Dysregulation in superoxide has previously been shown to increase intracellular oxidised mtDNA (oxmtDNA), which is thought to be pathogenic in SLE.20 To test whether superoxide dysregulation was associated with an increase in intracellular oxmtDNA in JDM CD14+monocytes, we used dot blot with densitometry to quantify 8-Hydroxy-2'-deoxyguanosine (8-OhDG) from mitochondria isolated from CD14+monocytes. Here, CD14 is linked to systemic lupus erythematosus.