Based on the H‐scores, we then divided these samples into high and low expression groups and determined the role of CD73 in tumor budding and circulating tumor cells (CTCs), which are established indicators for metastasis and prognosis of PDAC.[22, 23] The CD73 high expression group displayed a higher grade for budding (Figure 1I,J) and more CTCs than the low expression group (Figure 1K,L). Here, NT5E is linked to neoplasm.