RNF126 and invasive breast carcinoma: Our previous study suggests that RNF126 protein expression is upregulated in invasive breast cancer.[22] In addition, analyses using TCGA data showed that the expression level of RNF126 mRNA was not different among breast cancer subtypes (Figure S1E, Supporting Information); however, patients with high RNF126 expression displayed poorer prognosis than those with low RNF126 expression only in TNBC (Figure 1E).