To this end, we focused on four ccRCC patients representing different patterns of driver events (patient 1, multiple driver mutations [1MD]; patient 4, PTEN-mutated [4PTENm], patient 7, BAP1-mutated [7BAP1m]; and patient 11, no driver gene mutation detected [11ND]). This evidence concerns the gene BAP1 and nonpapillary renal cell carcinoma.