Tumor-related crucial glycoproteins (such as EGFR (2, 3), CD44 (4), E-cadherin (5), TGF-β receptor (6, 7), CA199 (8) and MUC-1 (9, 10)), glycan abundance and structural changes profoundly affect tumor cell fate and patient prognosis. This evidence concerns the gene EGFR and neoplasm.