CD274 and neoplasm: However, other factors including sex, age (≥60y vs <60y), tumor stage (locally advanced vs metastatic), treatment modality (monotherapy or combination), liver metastasis (yes vs no), treatment scenario (<2nd line vs ≥3rd line) and PD-L1 expression (TPS >30% vs ≤30%) did not seem to exert any significant influence on the OS of patients with pulmonary LELCs (Table 4).