TNFSF13B and graft versus host disease: To evaluate BAFF blockade in vivo, we established an acute GVHD mouse model (GVHD protocol 1) with irradiation at a dose of 800 cGy and IV injection of 5 × 106 bone marrow cells and 5 × 106 spleen cells from donor mice (C57BL/6, H-2Kb) as a basic GVHD research.