In our study, we found that the expressions of the seven Reelin pathway-related genes (CRK, DAB2IP, LRP8, RELN, STAT5A, CDK5R1, and FYN) were significantly correlated with some immune cell infiltration levels in AD patients, implying that these genes may play an important role in immune infiltrates of AD. This evidence concerns the gene LRP8 and Alzheimer disease.