After detecting the expression of PD-1 and LAG-3 in DLBCL tissues in 174 patients,we found that PD-1 and LAG-3 were widely expressed in TILs (Figure 1) and were correlated with bone marrow involvement.The expression of LAG-3 was also different at high and low LDH levels (Table 1). The gene discussed is PDCD1; the disease is diffuse large B-cell lymphoma.