These findings suggest that mitochondrial fission proteins such as DRP1, MFF, and FIS1 are likely to be reduced in people with sarcopenia, while exercise increases mitochondrial fission markers including DRP1, FIS1, and MFF (Hoffman et al., 2015; Yoo et al., 2018; Guan et al., 2019; Di Liu et al., 2021). This evidence concerns the gene FIS1 and sarcopenia.