Associated network functions: Cancer, protein synthesis, RNA damage and repair Number of “focus molecules” in the network: 22 IPA score: 46 Network proteins: 60S ribosomal subunit, ANKFY1, ASNS, Calmodulin, Ck2, CSTF2, DYNLL1, DYNLT3, estrogen receptor, G3BP1, GABARAPL2, H1-0,H2AZ2, Histone h4, LARP1, Lh, NDUFAF4, NFkB (complex), PCP4, PI3K (complex), PLC, PRKAR1B, PRPF19, PYM1, RAS, RNA polymerase II, Rnr, RPL23, RPL30, RPL35A, RPS12, RPS15A, SNU13, SUB1, Tgf beta. The gene discussed is ESR1; the disease is cancer.