PINK1 and Parkinson disease: This could signal an additional dimension of face validity for the Pink1–/– rat model, as impairments in cognition and memory typically present during prodromal phases of illness, i.e., before the onset of measurable motor deficits, in PD patients (Caviness et al., 2007; Pigott et al., 2015; Aarsland et al., 2017; Baiano et al., 2020; Fang et al., 2020).