The heatmap showed the relationship between high‐ and low‐risk groups and clinical features of glioma patients, such as gender, age, WHO grade, IDH mutation status, KPS, 1p/19q codeletion, TERT promoter status, and MGMT promoter methylation status, in TCGA database (Fig. 3A). The gene discussed is IDH1; the disease is central nervous system cancer.